Introduction: Children affected by parental HIV are more likely than unaffected peers to experience trauma and are at-risk for negative psychological and social outcomes. This study aimed to examine the relationship between adverse childhood events and psychosocial functioning among children affected by parental HIV.Methods: A total of 790 children ages 6–17 from Henan, China were enrolled in a longitudinal, randomized controlled trial of a resilience-based psychosocial intervention. At baseline, children reported on numerous psychosocial factors, including trauma exposure, symptoms of anxiety (...) and depression, and peer social functioning. We used linear regression analysis to test the direct effect of trauma exposure on peer social functioning. We then tested whether depression and anxiety symptoms served as two potential parallel mediators in the association between trauma exposure and peer social functioning.Results: Trauma exposure was significantly associated with poor peer social functioning when controlling for key covariates. When depression and anxiety symptoms were added to the model, the association between trauma exposure and peer social functioning became nonsignificant. Instead, there were significant indirect effects from trauma exposure to peer social functioning via depression and anxiety.Conclusion: This study is among the first to link trauma exposure to peer social functioning deficits for children affected by parental HIV and demonstrates that symptoms of anxiety and depression mediate this relationship. Findings underscore the need for comprehensive psychosocial support for children affected by HIV, including screening for trauma exposure and mental health disorders. (shrink)

Elymnion, according to Stephanos, was S000983880002084X_inline4 The name occurs in Aristophanes {Peace, 1126) in a context which points to the neighbourhood of Oreos. There is no evidence to connect it immediately with Chalkis. Mela mentions an Echinia near Akanthos: ' inter Strymona et Athon Turris Calarnaea et portus Capru, urbs Acanthos et Echinia.' Confusion of A and X is easy. Thus, even if the first sentence has no ol, the passage gives no safe evidence that these settlers came to Kleonai (...) from Chalkis, or from Euboea. Such a derivation would be hard to reconcile with Thucydides' account of the towns on Akte. If oί is right, cadit quaestio. (shrink)

Manuel des Études grecques et latines. ParL. Laurand. Fascicule VII.: Métrique, Sciences complémentaires (Critique des textes, Paléographie, Épigraphie, Numismatique, Histoire de la Philologie, Bibliographic, Le Travail philologique): 4e édition, revue et corrigée. Appendices II.-IV.: L'Art oratoire des anciens, L'Enseignement du grec et du latin, Lectures de litterature grecque et latine. Appendice V.: Petit atlas pratique d'histoire grecque et romaine. Paris: Auguste Picard, 1929. - Volume 45 Issue 2.

Ductin is the highest conserved membrane protein yet found in eukaryotes. It is multifunctional, being the subunit c or proteolipid component of the vacuolar H+‐ATPase and at the same time the protein component of a form of gap junction in metazoan animals. Analysis of its structure shows it to be a tandem repeat of two 8‐kDa domains derived from the subunit c of the F0 proton pore from the F1F0 ATPase. Each domain contains two transmembrane α‐helices, which together may form (...) a four‐helix bundle. In both the V‐ATPase and gap junction channel, ductin is probably arranged as a hexamer of subunits forming a central channel of gap junction‐like proportions. The two functions appear to be seggregated by ductin having two orientations in the bilayer. Ductin is also the major component of the mediatophore, a protein complex which may aid in the release of neurotransmitters across the pre‐synaptic membrane. It is also a target for a class of poorly understood viral polypeptides. These polypeptides are small and highly hydrophobic and some have oncogenic activity. Ductin thus appears to be at the crossroads of a number of biological processes. (shrink)